Hazards in Antihypertension Therapy

Comments1 January 1977Hazards in Antihypertension TherapyRUSSELL L. BERDOFF, M.D., RICHARD L. CHALAL, M.D., MICHAEL MADDENRUSSELL L. BERDOFF, M.D., RICHARD L. CHALAL, M.D., MICHAEL MADDENAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-1-111_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: A letter from Cohen and colleagues (1) in your August issue discussed the danger of antihypertension therapy with nitroprusside and clonidine. We have recently treated a patient with nitroprusside and methyldopa and met similar difficulty.A 71-year old black woman came to the emergency room complaining of mild ankle trauma. She gave a 30-year history of hypertension controlled by "one pill daily," but had taken no medications for 3 months. She had no symptoms of hypertension. Blood pressure was 250/150 mmHg and pulse, 102 beats/min. Fundi showed severe arteriolar narrowing with no hemorrhages or exudates, and flat...Reference1. COHEN I, MOTTET M, and FRANCIS G: Dangers in nitroprusside therapy. Ann Intern Med 85:205-206, 1976 LinkGoogle Scholar1. KANADA S, KANADA D, and HUTCHINSON R: Angina-like syndrome with diazoxide therapy for hypertensive crisis. Ann Intern Med 84:696-699, 1976 LinkGoogle Scholar2. MROCZEK W and LEE W: Diazoxide therapy: use and risks (letter). Ann Intern Med 85:529, 1976 LinkGoogle Scholar3. KUMAR G, DASTOOR F, and ROBAYO J: Side effects of diazoxide. JAMA 235:275-276, 1976 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RUSSELL L. BERDOFF, M.D.; RICHARD L. CHALAL, M.D.; MICHAEL MADDENAffiliations: The Georgetown University Medical Division District of Columbia General Hospital Washington, DC 20003 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySodium nitroprussidePathophysiology, clinical aspects, and treatment of hypertensive crisesFatal hypotension in normal-dose nitroprusside therapyHypotensive drugs 1 January 1977Volume 86, Issue 1Page: 111-112KeywordsAnklesBlood pressureEmergency departmentHeart rateHemorrhageHypertension ePublished: 1 December 2008 Issue Published: 1 January 1977 PDF downloadLoading ...