Key result
Anticardiolipin antibody positivity in women undergoing IVF-ET was associated with a significantly lower pregnancy rate (31.3% vs 48.6%) and higher incidence of pregnancy loss (32.0% vs 15.1%).
Why the study?
Does anticardiolipin antibody positivity affect the outcome of IVF-ET in infertile women?
Cohort (n=895)
No
Does anticardiolipin antibody positivity affect the outcome of IVF-ET in infertile women?
Absolute Event Rate: 31.3% vs 48.6%
Anticardiolipin antibody positivity is associated with significantly poorer outcomes in women undergoing IVF-ET for tubal factor infertility.
No takes yet. Share an insight, caveat, or question.
May warrant closer monitoring in IVF-ET; Level 3 evidence leaves open whether testing or intervention improves outcomes.
Zhong et al. (2011) conducted a cohort in Pure tubal factor infertility (n=895). Anticardiolipin antibody (ACA) positivity vs. Anticardiolipin antibody (ACA) negativity was evaluated on Pregnancy rate. Anticardiolipin antibody positivity in women undergoing IVF-ET was associated with a significantly lower pregnancy rate (31.3% vs 48.6%) and higher incidence of pregnancy loss (32.0% vs 15.1%).
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