Key result
Anticardiolipin antibodies are detected in 20% of women with at least three consecutive spontaneous abortions.
Why the study?
Is the prevalence of anti-cardiolipin antibody higher in women with habitual abortions compared to women with successful pregnancies?
Population
40 women: 20 patients with at least 3 consecutive spontaneous abortions and 20 women with at least one live…
Comparison
Enzyme-linked immunosorbent assay for detection… vs Women with at least one live birth without…
Design
Case-control
Authors
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Elevated ACA may flag recurrent abortion risk; Level 5 data leaves open diagnostic utility pending validation.
Case-Control (n=40)
Is the prevalence of anti-cardiolipin antibody higher in women with habitual abortions compared to women with successful pregnancies?
Absolute Event Rate: 20% vs 0%
Anti-cardiolipin antibodies are more prevalent in women with habitual abortions, particularly those occurring after the first trimester.
Costa et al. (2010) conducted a case-control in Habitual abortion (n=40). Habitual abortion history vs. At least one live birth without pregnancy wastage was evaluated on Detection of anticardiolipin antibody (ACA). Anticardiolipin antibody was detected in 20% of women with at least 3 consecutive spontaneous abortions, compared to 0% of women with at least one live birth without pregnancy wastage.
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