Why the study?
Does the presence of anticardiolipin antibodies (ACA) reduce the chance of live birth in women with recurrent miscarriage who are negative for lupus anticoagulant?
Population
147 women with unexplained recurrent miscarriage who were negative for lupus anticoagulant and did not…
Comparison
Repeatedly positive anticardiolipin antibodies… vs ACA negative
Design
Cohort
Follow-up
Through next pregnancy
Authors
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ACA positivity associated with lower live birth; leaves open whether testing or treatment alters outcomes in recurrent miscarriage.
Does the presence of anticardiolipin antibodies (ACA) reduce the chance of live birth in women with recurrent miscarriage who are negative for lupus anticoagulant?
In women with recurrent miscarriage who are negative for lupus anticoagulant, the presence of anticardiolipin antibodies significantly reduces the chance of live birth in the subsequent pregnancy.
Nielsen et al. (2005) studied this question.
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