Why the study?
Does co-induction with midazolam affect postoperative psychomotor recovery in patients undergoing day-case anaesthesia with propofol and alfentanil?
Population
48 patients undergoing day-case anaesthesia
Comparison
Midazolam 0.03 mg.kg-1 administered 2 minutes… vs Saline administered 2 minutes before induction…
Design
RCT, double blind
Follow-up
immediate postoperative phase
Authors
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Midazolam co-induction impairs early psychomotor recovery in day-case anesthesia; extends evidence on propofol sparing versus recovery trade-offs.
Does co-induction with midazolam affect postoperative psychomotor recovery in patients undergoing day-case anaesthesia with propofol and alfentanil?
Co-induction with midazolam reduces the required propofol induction dose but impairs immediate postoperative psychomotor recovery in day-case anesthesia.
Tighe et al. (1997) studied this question.
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