Population
Ventricular trabeculae from rat heart, chemically skinned with Triton X-100
Comparison
Alteration of bathing solution pH and addition… vs Control responses at pH 7.0 without added…
Design
Preclinical
Authors
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May attenuate rigor in ischemic muscle; leaves open clinical translation to human myocardial protection.
The fall in intracellular pH and rise in inorganic phosphate during ischemia may partially inhibit the development of rigor contracture in ventricular muscle.
Smith et al. (1994) studied this question.
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