Why the study?
Does the presence of intact chordae tendineae increase ventricular volume measurement error by the balloon method in formalin-fixed canine left ventricles?
Does the presence of intact chordae tendineae increase ventricular volume measurement error by the balloon method in formalin-fixed canine left ventricles?
Intact chordae tendineae significantly increase left ventricular volume measurement error by the balloon method due to the residual space behind the tense chordae.
Answers are grounded in this paper and cite their sources.
May bias ex vivo balloon LV volumetry upward with intact chordae; leaves open relevance to in vivo or human applications.
We assessed the accuracy of the intraventricular balloon method of left ventricular volume measurement with all chordae tendineae intact and then severed. The space between the endocardium and the balloon is the source of the volume measurement error. We assessed the volume errors at different intra-balloon pressures between 50 and 250 mmHg, using formalin fixed canine left ventricles. The volume error with all chordae tendineae intact was significantly greater than with all chordae tendineae severed at any balloon pressure. The difference of the volume errors under these two conditions amounted to 1.9-3.3 ml regardless of intra-balloon pressures. We visually confirmed that this difference predominantly originated from the space behind the tense chordae tendineae.
No takes yet. Share an insight, caveat, or question.
Tanaka et al. (1987) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: