Key result
The intraventricular balloon method accurately measures left ventricular volume in the rabbit, with the unmeasured space being only 1.5-3.6% of total volume at intraballoon pressures of 40-160 mmHg.
Population
8 Formalin-fixed rabbit left ventricles
Design
Preclinical
Authors
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Enables precise LV volumetry in rabbit models; leaves open translation to other species or clinical use.
The intraventricular balloon method provides accurate left ventricular volume measurements in small animal models like rabbits, particularly at higher intraballoon pressures.
Goto et al. (1988) studied Left ventricular volume measurement (n=8). Intraventricular balloon method was evaluated on Space between the balloon inflated in the left ventricle and the endocardial surface. The intraventricular balloon method accurately measures left ventricular volume in the rabbit, with the unmeasured space being only 1.5-3.6% of total volume at intraballoon pressures of 40-160 mmHg.
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