Key result
Intrauterine transvenous cardiac pacing at 200 beats/min decreased right ventricular output from 107 to 78.3 mL/kg per min without increasing tricuspid valve regurgitation.
Why the study?
Does intrauterine transvenous cardiac pacing affect right ventricular output in fetal lambs?
Does intrauterine transvenous cardiac pacing affect right ventricular output in fetal lambs?
Absolute Event Rate: 78.3% vs 107%
Intrauterine transvenous cardiac pacing is feasible in a fetal lamb model but decreases right ventricular output without increasing tricuspid regurgitation.
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Alerts to hemodynamic risks with fetal pacing; hypothesis-generating in lambs and leaves open human translation.
Kikuchi et al. (1995) studied Fetal complete heart block (n=6). Intrauterine transvenous cardiac pacing vs. Pacing lead in superior vena cava (control) was evaluated on Right ventricular output. Intrauterine transvenous cardiac pacing at 200 beats/min decreased right ventricular output from 107 to 78.3 mL/kg per min without increasing tricuspid valve regurgitation.
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