Key result
Higher flow rates during in vitro radio-frequency cardiac catheter ablation resulted in significantly larger lesion dimensions (p<0.01).
Why the study?
Does higher flow rate increase lesion dimensions during temperature-controlled RF cardiac catheter ablation in an in vitro bovine myocardium model?
Population
In vitro bovine myocardium model in a simulated heart chamber flow system
Comparison
Radio-frequency cardiac catheter ablation in… vs 0 L/min flow rate (no flow)
Design
Preclinical
Authors
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Hypothesis-generating for flow effects on lesion size in temperature-controlled RF ablation; requires in vivo confirmation before clinical consideration.
Does higher flow rate increase lesion dimensions during temperature-controlled RF cardiac catheter ablation in an in vitro bovine myocardium model?
p-value: p=<0.01
Higher simulated blood flow rates during temperature-controlled RF ablation result in larger lesion dimensions and faster tissue temperature rise.
Cao et al. (2001) studied Radio-frequency cardiac catheter ablation. High flow rates (1 L/min and 3 L/min) vs. 0 L/min flow rate was evaluated on Lesion dimensions (maximum depth, maximum width and lesion volume) (p=<0.01). Higher flow rates during in vitro radio-frequency cardiac catheter ablation resulted in significantly larger lesion dimensions (p<0.01).
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