Why the study?
Is percutaneous implantation of an aortic valve bioprosthesis feasible in a patient with severe calcific aortic stenosis?
Is percutaneous implantation of an aortic valve bioprosthesis feasible in a patient with severe calcific aortic stenosis?
This landmark report describes the first successful percutaneous implantation of an aortic valve bioprosthesis in a human, establishing the feasibility of transcatheter aortic valve replacement (TAVR).
Hypothesis-generating for transcatheter aortic valve replacement in severe aortic stenosis; leaves open safety, durability, and broader applicability pending prospective trials.
In April 2002, after extensive ex-vivo and animal implantation studies, we performed the first successful implantation of a new percutaneous aortic valve in a patient with endstage aortic stenosis. The purpose of this article is to give a detailed description of the technique of percutaneous implantation of aortic valve bioprosthesis in patients with severe calcific aortic stenosis. Antegrade transeptal approach was used under local anesthesia and mild sedation.
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Eltchaninoff et al. (2003) studied this question.
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