Key result
Novel self-expanding aortic valve prosthesis demonstrates successful preclinical transcatheter implantation.
Why the study?
Existing self-expanding aortic valve models have significant drawbacks, motivating development of a new prototype for patients with calcific aortic stenosis contraindicated for open surgery.
Demonstrates the initial experimental feasibility of a novel self-expanding transcatheter aortic valve prototype.
Answers are grounded in this paper and cite their sources.
Successful animal implantation supports prototype development; leaves open human translation and clinical testing.
Calcific aortic stenosis is an aortic valve disease of atherosclerotic origin occurring in 2-4 % of persons older than 65 years, for whom open surgery is contraindicated. Models of self-expanding aortic valves available today have a number of significant drawbacks. The authors have developed a prototype of a new aortic valve and present its first successful implantation in the experiment.
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Kretov et al. (2016) studied Calcific aortic stenosis. Prototype of a new self-expanding aortic valve prosthesis was evaluated on Successful implantation. A prototype of a new self-expanding aortic valve prosthesis was successfully implanted in an experimental setting.
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