Key result
Body fat mass in superobese pre-pubertal boys showed a weak but significant positive correlation with hsCRP levels (r= +0.383; P<0.0001), but no correlation with adipocytokine levels.
Why the study?
Obesity causes adipocytokine dysregulation and promotes pro-inflammatory responses linked to cardiometabolic diseases, motivating evaluation of low-grade chronic inflammation and its correlation with adipocytokines and body fat mass in pre-pubertal obese boys.
Cross-Sectional (n=80)
Effect estimate: r= +0.383
p-value: p=<0.0001
Low-grade chronic inflammation begins at a young age in superobese boys and correlates weakly with body fat mass, highlighting the need for early prevention of childhood obesity to mitigate future cardiometabolic risk.
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Suggests early inflammation in obese pre-pubertal boys; hypothesis-generating and requires longitudinal data before clinical relevance.
Hendarto et al. (2019) conducted a cross-sectional in Childhood obesity (n=80). Body fat mass was evaluated on Correlation between hsCRP level and body fat mass (r= +0.383, p=<0.0001). Body fat mass in superobese pre-pubertal boys showed a weak but significant positive correlation with hsCRP levels (r= +0.383; P<0.0001), but no correlation with adipocytokine levels.
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