Population
Smooth muscle cells isolated from the rat vas deferens
Comparison
Extracellular ATP and structural analogues vs Absence of ATP or other structural analogues
Design
Preclinical
Authors
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May underlie ATP depolarization in rodent vas deferens; leaves open purinergic roles in human smooth muscle physiology.
Extracellular ATP elicits a rapid, desensitizing, cation-selective inward current in rat vas deferens smooth muscle cells, which may be responsible for its depolarizing effect.
D D Friel (1988) studied this question.
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