Why the study?
Sierra Leone reported its last wild polio case in 2010, but in December 2020 three people with acute flaccid paralysis were confirmed to have cVDPV2, prompting an investigation into the outbreak's source, magnitude, and risk factors.
The outbreak of cVDPV2 in Sierra Leone was likely facilitated by low routine immunization coverage and poor cold chain management, highlighting the urgent need for strengthened surveillance and vaccination programs.
Circulating Vaccine Derived Poliovirus (cVDPV), is a genetic mutation of the Sabin virus. Sierra Leone reported its last case of wild polio virus in 2010. However, in December 2020, the national disease surveillance program was notified of three people with acute flaccid paralysis who had cVDPV2. We investigated to identify the source, determine the magnitude of the outbreak and risk factors.
No takes yet. Share an insight, caveat, or question.
Alhaji et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: