Population
Conscious, unrestrained, male, Long Evans rats, chronically instrumented for the measurement of regional…
Comparison
Glyceryl trinitrate or molsidomine, administered… vs Baseline or control conditions without the…
Design
Preclinical
Authors
Loading...
Caution against extrapolating nitrate effects to patients; leaves open clinical relevance of RAS-NO interactions in humans.
The renin-angiotensin system and endogenous nitric oxide modulate the regional haemodynamic responses to exogenous nitric oxide donors like glyceryl trinitrate and molsidomine in conscious rats.
Phillips et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: