Why the study?
Does Coxsackie B3 virus infect human pancreatic beta cells and affect insulin levels in vitro?
Population
Human pancreatic beta cell cultures
Comparison
Infection with Coxsackie B3 virus vs Uninfected human pancreatic beta cells
Design
Preclinical
Follow-up
24 hours
Authors
Loading...
Suggests possible viral beta-cell effects in models; leaves open relevance to human diabetes pathogenesis.
Does Coxsackie B3 virus infect human pancreatic beta cells and affect insulin levels in vitro?
This study provides in vitro evidence that human pancreatic beta cells are susceptible to Coxsackie B3 virus infection, which leads to a decrease in intracellular insulin.
Yoon et al. (1978) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: