Why the study?
Does Coxsackie virus B4 infection induce beta cell damage and hyperglycemia in mice?
Population
SJL/J mice and other inbred strains of mice
Design
Preclinical
Follow-up
60 days
Authors
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Provides murine model for virus-induced diabetes; human relevance remains to be established.
Does Coxsackie virus B4 infection induce beta cell damage and hyperglycemia in mice?
Coxsackie virus B4 infection can induce beta cell destruction and a transient diabetes-like syndrome in susceptible mouse strains, providing a model for virus-induced diabetes.
Yoon et al. (1978) studied this question.
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