Why the study?
Can a colorimetric neutralization test detect group B Coxsackie virus infections in patients with central nervous system disease?
Population
540 patients with central nervous system disease
Design
Cross-sectional
Authors
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Supports colorimetric neutralization testing when isolation unavailable; leaves open prospective validation in CNS disease.
Can a colorimetric neutralization test detect group B Coxsackie virus infections in patients with central nervous system disease?
The colorimetric neutralization test is useful for diagnosing group B Coxsackie virus infections, particularly when viral isolation is not possible.
Lennette et al. (1961) studied this question.