Why the study?
Does an IgM antibody capture radioimmunoassay accurately detect coxsackie B virus specific IgM without heterotypic cross-reactivity?
Population
Patients with coxsackie B virus infections and 37 patients with other enterovirus infections.
Design
Other
Authors
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May compromise diagnostic accuracy in enteroviral disease; challenges assay specificity and leaves open need for validation studies.
Does an IgM antibody capture radioimmunoassay accurately detect coxsackie B virus specific IgM without heterotypic cross-reactivity?
The IgM antibody capture radioimmunoassay for coxsackie B virus shows frequent heterotypic cross-reactivity with other enterovirus infections, limiting its specificity.
Simon Pugh (1984) studied this question.
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