January 1, 1983Journal of General Virology
Specificity of IgM Antibodies in Acute Human Coxsackievirus B Infections, Analysed by Indirect Solid Phase Enzyme Immunoassay and Immunoblot Technique
Population
Patients with acute human coxsackievirus B infections
Authors
Discussion
Loading...
Member takes
Implication
VP1-based IgM ELISA may support acute coxsackievirus B serology; leaves open prospective validation before clinical adoption in myocarditis evaluation.
Structured PICO
P
Population
Patients with acute human coxsackievirus B infections
I
Intervention
Indirect solid phase enzyme immunoassay (ELISA) and immunoblot techniques
O
Outcome
Specificity of the IgM responsesurrogate
VP1 is the major antigen in acute human coxsackievirus B infections, eliciting both homotypic and heterotypic IgM responses.
Cite This Study
Dörries et al. (1983) studied this question.