Population
Newborn mice used for inoculation; 6 laboratory workers who contracted Coxsackie virus infections; and…
Design
Preclinical
Follow-up
Up to 2 years
Authors
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Neutralization assays aid Coxsackie virus typing; extends antigenic classification but leaves open human clinical relevance.
The neutralization test is a reliable method for typing Coxsackie viruses and tracking neutralizing antibody responses, which appear rapidly after infection and persist for years.
Melnick et al. (1950) studied this question.
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