Why the study?
Enterovirus D68 emerged as a cause of severe respiratory disease occasionally leading to paralysis, motivating evaluation of changes in its seroprevalence.
The incidence of enterovirus D68 infections in young children in the UK increased significantly between 2006 and 2016, coinciding with the emergence of severe respiratory and neurological disease.
Rising EV-D68 seroprevalence in UK children by 2016 may heighten vigilance; leaves open need for surveillance or vaccines.
We determined the change in seroprevalence of enterovirus D68 (EV-D68) in the United Kingdom in age-stratified cohorts from 2006 to 2016, the period during which EV-D68 emerged as a cause of severe respiratory disease occasionally leading to paralysis. Infections were acquired primarily in infants and young children, and incidence was markedly higher in 2016.
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Kamau et al. (2019) studied this question.
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