Why the study?
Does human interferon inhibit type D retrovirus multiplication in chronically infected cell lines?
Population
Chronically infected human cell lines with type D viruses (MPMV and SMRV)
Comparison
Human interferon at concentrations of 50 IU/ml vs Control cells (untreated)
Design
Preclinical
Authors
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In vitro interferon effects on type D retrovirus release remain untested clinically; extends prior type C/B observations but should not change practice.
Does human interferon inhibit type D retrovirus multiplication in chronically infected cell lines?
Human interferon inhibits the release of type D retroviruses from chronically infected human cell lines, similar to its effect on type C and B retroviruses.
Canivet et al. (1983) studied this question.
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