The study demonstrates that brown fat tissue in albino mice can promptly regenerate following damage from Coxsackie B-1 virus infection or localized freezing.
This is the authors' abstract. We don't add key points for this paper.
Prompt regeneration of brown fat tissue in the albino mouse is observed following experimental infection with Coxsackie B-l virus. The sequence of changes is recorded in detail.The inflammatory response and regenerative process differ in the central and peripheral zones of the brown fat lobules. Cell lysis is predominant in the central zone while a necrotic process often accompanied by the formation of lipogran-ulomas is seen in the peripheral zones.Similar inflammatory and regenerative changes are observed following localized damage of the brown fat tissue inflicted by freezing.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for brown fat regeneration in mice; leaves open any translational relevance to human cardiometabolic disease.
No takes yet. Share an insight, caveat, or question.
Grodums et al. (1963) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: