Population
Developing rat kidney and adrenal gland (from day 12 of fetal life to adulthood)
Design
Preclinical
Authors
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Rodent AT2 expression patterns should not guide clinical decisions in renal development; leaves open its role as a differentiation factor in humans.
The transient expression of AT2 receptors during nephrogenesis and continuous expression in the adrenal gland suggests ANG II acts as a differentiation and growth factor via this receptor.
Shanmugam et al. (1995) studied this question.
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