Population
17 open-chest adult mongrel dogs (weight 12-32 kg)
Comparison
Intracoronary infusion of adenosine, serotonin… vs Baseline control state before drug…
Design
Preclinical
Authors
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Preclinical findings on cardiac lymph flow should not alter practice; leaves open translational relevance to human coronary disease.
This preclinical study demonstrates that cardiac lymph flow increases with coronary blood flow increments induced by vasoactive drugs, while increased heart rate decreases lymph flow, likely due to shortened diastolic time.
M Hasui (1990) studied this question.
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