Risk of Incident Heart Failure in Patients With Diabetes and Asymptomatic Left Ventricular Systolic Dysfunction
Why the study?
Does diabetes increase the risk of developing symptomatic heart failure in patients with asymptomatic left ventricular systolic dysfunction?
Structured PICO
Does diabetes increase the risk of developing symptomatic heart failure in patients with asymptomatic left ventricular systolic dysfunction?
P
Population
4,223 patients with asymptomatic left ventricular systolic dysfunction (ALVSD) from the prevention arm of the Studies of Left Ventricular Dysfunction (SOLVD-P)
I
Intervention
Diabetes at baseline
C
Comparator
No diabetes at baseline
O
Outcome
Development of symptomatic heart failurehard clinical
In patients with asymptomatic left ventricular systolic dysfunction, the presence of diabetes significantly increases the risk of progressing to overt, symptomatic heart failure and heart failure hospitalization.
Authors
Discussion
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Implication
Diabetes associated with higher incident HF risk in ALVSD; leaves open whether targeted prevention alters outcomes in this population.
Cite This Study
Rørth et al. (2018) studied this question.