Population
Mechanically skinned fibres derived from soleus and extensor digitorum longus muscles of normal and…
Comparison
Calcium (Ca2+) and strontium (Sr2+) activation vs Normal vs dystrophic muscle fibres
Design
Preclinical
Authors
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No clinical action warranted from murine fiber differences; leaves open extension to human dystrophy mechanisms.
The study identifies significant physiological differences in the mechanism of force activation by Ca2+ and Sr2+ in murine muscular dystrophy compared to normal muscle fibers.
Fink et al. (1986) studied this question.
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