July 1, 1981Acta Physiologica Scandinavica

Role of adenosine in adipose tissue circulation

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Population

Subcutaneous adipose tissue in situ model

Design

Preclinical

Authors

ASAlf SolleviUniversidad Mayor BFBertil B. FredholmKarolinska Institutet

Discussion

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Implication

Leaves open adenosine's role in human adipose perfusion; further studies needed before considering therapeutic applications.

Structured PICO

Population

Subcutaneous adipose tissue in situ model

Intervention

Adenosine, 2- and 6-substituted analogues, adenosine uptake blockers (dipyridamole, dilazep), adenosine deaminase inhibitor (EHNA), and antagonists (theophylline, caffeine)

Outcome

Vasodilatory effect (tissue blood flow, vascular conductance, capillary filtration coefficient)surrogate

Adenosine acts as a potent vasodilator in subcutaneous adipose tissue, suggesting a physiological role in regulating adipose tissue blood flow.

Cite This Study

Sollevi et al. (1981) studied this question.

synapsesocial.com/papers/6a90e4e6d2f2d69b3a744cdb https://doi.org/10.1111/j.1748-1716.1981.tb06819.x

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Role of adenosine in adipose tissue circulation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Role of adenosine in adipose tissue circulation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider