Why the study?
Do circulating cytokine levels correlate with hemodynamic instability after pulmonary endarterectomy in patients with chronic thromboembolic pulmonary hypertension?
Do circulating cytokine levels correlate with hemodynamic instability after pulmonary endarterectomy in patients with chronic thromboembolic pulmonary hypertension?
Higher postoperative plasma concentrations of IL-6 and IL-8 are associated with hemodynamic instability and increased vasopressor requirements after pulmonary endarterectomy for CTEPH.
May signal inflammatory contribution to post-PEA instability in CTEPH; leaves open whether IL-6 targeting improves outcomes, needing prospective trials.
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Lindner et al. (2009) studied this question.
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