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March 30, 2017Scientific ReportsOpen Access

Reactive Hyperemia Index in Patients on Maintenance Hemodialysis: Cross-sectional Data from a Cohort Study

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Why the study?

What are the clinical determinants of the reactive hyperemia index (RHI) and its association with endothelial and cardiac markers in hemodialysis patients?

Population

368 patients on maintenance hemodialysis

Design

Cross-sectional

Authors

WLWenjin LiuUniversity of North Carolina at Chapel HillMMMeijuan MengWuxi People's HospitalJCJianping ChenNingbo University

Discussion

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Implication

RHI shows modest associations with select endothelial and troponin markers in hemodialysis; leaves open its added prognostic value beyond traditional risks.

Structured PICO

What are the clinical determinants of the reactive hyperemia index (RHI) and its association with endothelial and cardiac markers in hemodialysis patients?

P
Population
368 patients on maintenance hemodialysis
I
Intervention
Reactive hyperemia index (RHI) evaluation by peripheral arterial tonometry (PAT) on a midweek nondialysis day
O
Outcome
Clinical determinants of RHI and its association with circulating endothelial injury and cardiac markerssurrogate

In hemodialysis patients, traditional clinical variables have limited influence on RHI, which shows only modest associations with specific endothelial injury and cardiac markers.

Cite This Study

Liu et al. (2017) studied this question.

synapsesocial.com/papers/6a90f0a8504d7cdc493e7ea0https://doi.org/10.1038/srep45757
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