Population
Isolated tissues including guinea pig ileal longitudinal muscle strips, canine coronary artery, guinea pig…
Design
Preclinical
Authors
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Nifedipine and diltiazem may guide vascular-focused models; leaves open clinical translation of selectivity differences.
In isolated tissue models, nifedipine and diltiazem demonstrate greater selectivity for smooth muscle over cardiac muscle compared to verapamil.
Terry Kenakin (1985) studied this question.
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