Why the study?
Does sympathetic chain stimulation reduce the diameter of the abdominal aorta in anesthetized dogs?
Population
Anesthetized dogs
Comparison
Stimulation of the peripheral ends of the cut… vs Resting state / unilateral stimulation /…
Design
Preclinical
Authors
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Regional sympathetic aortic control confirmed in dogs; leaves open translation to human aortic disease.
Does sympathetic chain stimulation reduce the diameter of the abdominal aorta in anesthetized dogs?
Sympathetic stimulation induces a frequency-dependent reduction in canine abdominal aorta diameter with a significant proximo-distal gradient, which corresponds to regional sensitivity to norepinephrine rather than nerve terminal density.
Gerová et al. (1973) studied this question.
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