Population
Anaesthetized dogs, artificially ventilated (n=27)
Comparison
Localized stimulation of left atrial receptors… vs Baseline state and/or denervated kidneys
Design
Preclinical
Follow-up
23-25 minutes
Authors
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Renal nerve mediation of atrial-renal reflexes confirmed in animals; leaves open translation to human volume regulation or HF.
Renal sympathetic nerves mediate the primary short-term renal responses (increased blood flow, GFR, and sodium excretion) to left atrial receptor stimulation.
Karim et al. (1989) studied this question.
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