Why the study?
Does hypoglycemia alter functional connectivity of resting state networks differently in patients with type 1 diabetes compared to nondiabetic controls?
Population
Patients with type 1 diabetes and nondiabetic controls
Comparison
Sequential euglycemic-hypoglycemic clamp studies… vs Nondiabetic controls undergoing the same clamp…
Design
Other
Authors
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May reflect adaptive brain network changes during hypoglycemia in type 1 diabetes; hypothesis-generating and requires prospective validation before clinical relevance.
Does hypoglycemia alter functional connectivity of resting state networks differently in patients with type 1 diabetes compared to nondiabetic controls?
Type 1 diabetes alters brain functional connectivity in regions mediating interoceptive awareness and cognition during hypoglycemia, likely reflecting neuroplastic adaptations to frequent hypoglycemic excursions.
Bolo et al. (2015) studied this question.
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