Population
Mammalian cell lines expressing hSK1
Design
Preclinical
Authors
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hSK1 apamin sensitivity in mammalian cells leaves open native cardiac channel behavior; hypothesis-generating before targeting in arrhythmia models.
The pharmacological properties of hSK1 channels depend on the expression system, showing apamin sensitivity in mammalian cell lines unlike in Xenopus oocytes.
Shah et al. (2000) studied this question.
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