Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 1, 2005American Journal of Hypertension

Oral Amino Acid Administration Decreases Oxidative Stress and Improves Brachial Reactivity in Elderly Individuals

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does essential amino acid administration improve brachial reactivity and decrease oxidative stress in healthy elderly subjects?

Population

25 healthy elderly subjects

Comparison

Essential amino acids administered for 4 months vs Baseline (before EAA administration)

Design

Cohort

Follow-up

4 months

Authors

DMDaniela ManzellaRGRoberto GrellaKEKatherine Esposito

Discussion

Loading...

Member takes

Overview

May support EAA for endothelial function in healthy elderly; leaves open confirmation in randomized trials.

Structured PICO

Does essential amino acid administration improve brachial reactivity and decrease oxidative stress in healthy elderly subjects?

P
Population
25 healthy elderly subjects
I
Intervention
Essential amino acids (EAA) administered for 4 months
C
Comparator
Baseline (before EAA administration)
O
Outcome
Brachial reactivity (changes in diameter and flow) and oxidative stress markers (TEAC, TBARS)surrogate

Oral administration of essential amino acids for 4 months improves endothelial function and reduces oxidative stress in healthy elderly individuals.

Cite This Study

Manzella et al. (2005) studied this question.

synapsesocial.com/papers/6a910e48ea479158cc70fc66https://doi.org/10.1016/j.amjhyper.2004.12.006
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Effect of Supplementation with Essential Amino Acids on Cardiac Performance in Elderly Patients with Heart Failure and Sarcopenia2025 · 3 citations
  2. 2Ascorbic acid improves brachial artery vasodilation during progressive handgrip exercise in the elderly through a nitric oxide-mediated mechanism2016 · 29 citations
  3. 3Oral L-arginine improves endothelial function in healthy individuals older than 70 years2003 · 198 citations
  4. 4Endothelium‐dependent vasodilatation and exercise hyperaemia in ageing humans: impact of acute ascorbic acid administration2009 · 117 citations
  5. 5Effects of Oral Amino Acid Supplements on Functional Capacity in Patients with Chronic Heart Failure2014 · 31 citations