Why the study?
Does the ACE gene DD genotype increase QT dispersion in patients with hypertrophic cardiomyopathy?
Population
63 patients with hypertrophic cardiomyopathy (HCM) and 20 healthy control subjects
Comparison
Angiotensin-converting enzyme gene DD genotype vs Other ACE genotypes (II, ID) and healthy controls
Design
Case-control
Authors
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DD genotype associated with greater QT dispersion in HCM; hypothesis-generating for arrhythmic risk, needs prospective validation.
Does the ACE gene DD genotype increase QT dispersion in patients with hypertrophic cardiomyopathy?
The ACE gene DD genotype is associated with increased QT dispersion in patients with hypertrophic cardiomyopathy, suggesting a potential genetic marker for increased arrhythmic risk.
Kaya et al. (2010) studied this question.
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