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January 1, 1974Cold Spring Harbor Symposia on Quantitative Biology

The Cell-free Translation of SV40 Messenger RNA

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Population

SV40 virus and virus-transformed cells

Design

Preclinical

Authors

CPCarol PrivesScripps Research InstituteHAHaim AvivWeizmann Institute of ScienceEGEli GilboaUniversity of Miami

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Implication

May advance SV40 protein detection in animal models; leaves open relevance to human cardiovascular disease.

Structured PICO

P
Population
SV40 virus and virus-transformed cells
I
Intervention
Cell-free translation of SV40 messenger RNA
O
Outcome
Identification of virus-coded proteins

The study aims to establish a method for identifying SV40 virus-coded proteins to understand the virus-induced transformation process.

Cite This Study

Prives et al. (1974) studied this question.

synapsesocial.com/papers/6a912236f61bbdbd5ac1bda5https://doi.org/10.1101/sqb.1974.039.01.041
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Altered Patterns of Protein Synthesis in Infection by SV40 Mutants1974 · 89 citations
  2. 2Requirement for the Large T and Small T Proteins of SV40 in the Maintenance of the Transformed State1980 · 49 citations
  3. 3SV40-Specific RNA in the Nucleus and Polyribosomes of Transformed Cells1970 · 108 citations
  4. 4The Detection and Quantitation of SV40 Nucleic Acid Sequences Using Single-stranded SV40 DNA Probes1974 · 29 citations
  5. 5Regulation of transcription of the SV40 DNA in productively infected and in transformed cells.1968 · 143 citations