Why the study?
Does treadmill exercise elicit exaggerated blood pressure and heart rate responses in spontaneously hypertensive rats compared to renal hypertensive rats?
Population
Spontaneously hypertensive rats (SHR) and renal hypertensive rats (RHR)
Comparison
Treadmill exercise vs Renal hypertensive rats (RHR) or baseline
Design
Preclinical
Authors
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May inform model selection for hypertension research; leaves open translation to human exercise responses.
Does treadmill exercise elicit exaggerated blood pressure and heart rate responses in spontaneously hypertensive rats compared to renal hypertensive rats?
In experimental models of hypertension, spontaneously hypertensive rats exhibit slight hyper-responsiveness in heart rate to exercise, while renal hypertensive rats respond normally.
Baum et al. (1975) studied this question.
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