Why the study?
Do anticoagulants prevent systemic embolism in patients undergoing mitral valvotomy?
Do anticoagulants prevent systemic embolism in patients undergoing mitral valvotomy?
This nine-year survey evaluates the use of anticoagulants to prevent systemic embolism during and after mitral valvotomy.
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Observational data on anticoagulants for embolism prevention in mitral valvotomy support further evaluation; leaves open need for randomized confirmation before practice change.
Systemic embolism, occurring during either the operation or in the post-operative period, remains a serious complication of mitral valvotomy. It causes many deaths and those who survive it may suffer a crippling permanent disability. Since 1955 anticoagulants have been widely used at the Hill Top Hospital, Bromsgrove, for the purpose of preventing clot formation and subsequent dis- semination at operation, and the results of this therapy form the basis of this study.
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Sunil Stephenson (1966) studied this question.
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