Children with type 1 diabetes exhibit an impaired type 1 immune response to Coxsackie virus B4, which may explain their susceptibility to CVB4 infections and related beta-cell damage.
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May indicate heightened CVB4 vulnerability in T1D youth; hypothesis-generating for viral-autoimmunity links, needing prospective validation.
Skarsvik et al. (2006) studied this question.
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