Why the study?
Does a community-wide oral poliovirus vaccination program impact the circulation of enteroviruses in the community?
Population
Two small New England cities, including sewage specimens and rectal swabs from infants and preschool…
Design
Cohort
Follow-up
7 years
Authors
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Supports contact spread of vaccine-derived strains in OPV programs; leaves open effects on enterovirus ecology and requires prospective confirmation.
Does a community-wide oral poliovirus vaccination program impact the circulation of enteroviruses in the community?
Continuous use of oral poliovirus vaccine leads to dissemination of vaccine strains through contact infection, likely raising herd immunity among susceptible children without affecting other enteroviruses.
Horstmann et al. (1973) studied this question.
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