Why the study?
Are the kidneys responsible for the removal of immunoreactive GIP in humans and rats?
Population
10 patients undergoing routine cardiac catheterization, and 16 rats (8 nephrectomized, 8 control)
Comparison
Measurement of plasma GIP across different… vs Hepatic vein, right atrium, femoral vein, and…
Design
Other
Follow-up
60 minutes (rats)
Authors
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Suggests kidneys clear GIP; hypothesis-generating for incretin effects in renal impairment.
Are the kidneys responsible for the removal of immunoreactive GIP in humans and rats?
This study demonstrates that the kidneys play a significant role in the removal and clearance of immunoreactive GIP from the circulation in both humans and rats.
Jorde et al. (1981) studied this question.
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