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July 1, 1990Anesthesia & Analgesia

Intestinal Hemodynamics During Laparotomy

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Why the study?

Does dopamine infusion improve superior mesenteric artery blood flow during thoracic epidural anesthesia in patients undergoing abdominal aortic reconstruction?

Population

9 patients before abdominal aortic reconstruction

Comparison

Thoracic epidural anesthesia and dopamine infusion vs Baseline (control) before TEA

Design

Other

Authors

JLJ. LundbergSkåne University HospitalDLDag LundbergSkåne University HospitalLNLars NorgrenVascular / Pulmonary Vascular

Discussion

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Implication

May support mesenteric perfusion with dopamine during TEA; hypothesis-generating for outcomes in aortic reconstruction.

Structured PICO

Does dopamine infusion improve superior mesenteric artery blood flow during thoracic epidural anesthesia in patients undergoing abdominal aortic reconstruction?

P
Population
9 patients before abdominal aortic reconstruction
I
Intervention
Thoracic epidural anesthesia (TEA) and dopamine infusion (4 micrograms.kg-1.min-1)
C
Comparator
Baseline (control) before TEA
O
Outcome
Superior mesenteric artery blood flow (SMABF), mesenteric arteriovenous oxygen difference (AVDO2), and mesenteric venous lactate concentrationsurrogate

Dopamine infusion improves intestinal blood flow and reverses reductive metabolism caused by decreased perfusion pressure during thoracic epidural anesthesia.

Cite This Study

Lundberg et al. (1990) studied this question.

synapsesocial.com/papers/6a91421035eca4d44dab4d93https://doi.org/10.1213/00000539-199007000-00002
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hemodynamic Effects of Dopamine during Thoracic Epidural Analgesia in Man1987 · 47 citations
  2. 2Thoracic Epidural Anesthesia Increases Mucosal Perfusion in Ileum of Rats2000 · 112 citations
  3. 3Intestinal effects of thoracic epidural anesthesia2009 · 44 citations
  4. 4Effects of Thoracic Epidural Anesthesia on Systemic Hemodynamic Function and Systemic Oxygen Supply-Demand Relationship1989 · 46 citations
  5. 5The Effects of Thoracic Epidural Anesthesia on Intraoperative Visceral Perfusion and Metabolism1999 · 50 citations