Population
6- and 9-week-old Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR)
Comparison
Measurement of pressure-flow curves and… vs Normotensive Wistar-Kyoto (WKY) rats
Design
Preclinical
Authors
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Preserved autoregulation in SHR models warrants no clinical practice change; leaves open structural mechanisms for human vascular resistance.
Acute autoregulatory responses in skeletal muscle are preserved during the development of hypertension in spontaneously hypertensive rats, supporting a structural basis for chronically elevated peripheral vascular resistance.
Alson et al. (1985) studied this question.
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