Large, reactive platelets are more sensitive to ADP but have a lower maximal aggregation rate, suggesting they are not hyperaggregable in a kinetic sense.
No takes yet. Share an insight, caveat, or question.
Higher ADP sensitivity but lower Vmax in large platelets; challenges uniform hyperaggregability and leaves open in vivo thrombotic relevance.
Haver et al. (1982) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: