Population
Pump-oxygenator perfused dogs
Comparison
Separately pressurizing the pulmonary vessels… vs Left heart baroreflex; baseline vasomotor tone
Design
Preclinical
Authors
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Hypothesis-generating for pulmonary pressure-mediated reflexes in animal models; leaves open human translation and clinical relevance.
In a canine model, pulmonary vascular pressurization induces transient systemic vasodilation, but pulmonary edema does not significantly alter systemic vasomotor tone.
T. C. Lloyd (1977) studied this question.