Why the study?
Does oral calcium supplementation reduce blood pressure in specific renin subgroups of essential hypertensive subjects?
Population
Subjects with essential hypertension
Design
Review
Authors
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Hypothesis-generating for renin-subgroup calcium effects on BP; leaves open prospective RCT confirmation before any clinical consideration.
Does oral calcium supplementation reduce blood pressure in specific renin subgroups of essential hypertensive subjects?
Calcium metabolism and regulating hormones may interact with the renin-aldosterone system to influence blood pressure and response to antihypertensive therapy in essential hypertension.
Resnick et al. (1985) studied this question.
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